After starting his banking career in with Chase National Bank Egypt, Dr. Seyam became general manager of Commercial International Bank, then moved to HSBC Bank Egypt as general manager for corporate banking. He then became chairman of HSBC securities in Egypt and in 2011, became managing director and deputy CEO for HSBC Bank Egypt. The same year, he was appointed chairman and CEO of Banque du Caire. Since June 2012, he has served as chairman of the Supervisory Board at Banque Misr Europe. Seyam also served as chairman of the Egyptian Stock Market Authority (2008-2009), vice chairman of the Stock Market Financial Supervisory Authority (2009-2010), and chairman of the Stock Exchange (2010-2011). He was also executive director of the Financial Services Institute (2011-2013).
As senior legal advisor to the ministers of foreign trade and finance, and senior legal advisor to the Private Public Partnership (PPP) unit, Seyam led the drafting of the PPP law, and supervised the legal tender procedures for the first major PPP projects in education, health, and wastewater. In addition, he sat on the boards of directors of the General Authority of Investment and Free Zones (GAFI); the Information Technology Industry Development Agency (ITIDA); the Misr Settlement, Depository and Clearing Company (MCDR); the Egyptian Mortgage Refinance Company (EMRC); and the Arab Moltaqa Investment Company (AMIC).
Seyam took part in drafting several Egyptian laws and advised several governments and international institutions on matters of legal reforms. including Jordan, Yemen, Bahrain, Kenya, Libya, the World Bank, and the World Health Organization. He also played a major role in the founding of the Financial Service Institute (FSI). In collaboration with Jean Moulin University, Lyon 3, Seyam helped create the French section of the Faculty of Law at Ain Shams University. He holds a PhD from Jean Moulin University, France and an LLB from Ain Shams University.